microM^-1*min^-1, Table 1 in Sonntag et al, 2012 min^-1, Table 1 in Sonntag et al, 2012 microM^-3*min^-1 min^-1 min^-1, like K_CaMKII_toCaMKII_in microM^-1*min^-1, like K_CaMKIIin_toCaMKII microM^-1*min^-1 min^-1 initial was 0.3,n.u. 0.01 microM initial was 0.02,microM microM 0.005 0.001 initial was 0.01, min^-1 initial was 0.01, min^-1 was 0.05 was 0.05 microM/min initial was 0.1,n.u. n.u. n.u. n.u., reflects activation of Ca increase, Ca concentraton at exercise is 0.5 microM $\mathrm{K\_basal\_NR4A3}+\mathrm{delay}(\mathrm{NR4A3\_gene\_mRNA}, 0.5)-\mathrm{K\_degr\_mRNA\_nr4a3}\mathrm{NR4A3\_mRNA}$ $\mathrm{K\_CaCaM\_assos}\mathrm{Calmodulin}\mathrm{k\_ex}^{2.0}\mathrm{Ca2\_}^{2.0}-\mathrm{K\_CaCaM\_diss}\mathrm{Ca\_Calmodulin}$ $\mathrm{K\_CaMKIIin\_toCaMKII}\mathrm{CaMKII\_in}\mathrm{Ca\_Calmodulin}-\mathrm{K\_CaMKII\_toCaMKII\_in}\mathrm{CaMKII}$ $\mathrm{K\_CaMKKIIin\_toCaMKKII}\mathrm{CaMKKII\_in}\mathrm{Ca\_Calmodulin}-\mathrm{K\_CaMKKII\_toCaMKKIIin}\mathrm{CaMKKII}$ $\mathrm{K\_CaNin\_toCaN}\mathrm{Calcineurin\_in}\mathrm{Ca\_Calmodulin}-\mathrm{K\_CaN\_toCaNin}\mathrm{Calcineurin}$ $\mathrm{K\_AMPKin\_toAMPKp}\mathrm{AMPK\_2\_2\_3}\mathrm{CaMKKII}-\mathrm{K\_AMPKp\_toAMPKin}\mathrm{AMPK\_2\_2\_4}$ $\mathrm{K\_PGC1alpha\_toPGC1alphap}\mathrm{PGC\_1alpha}\mathrm{AMPK\_2\_2\_4}-\mathrm{K\_PGC1alphap\_toPGC1alpha}\mathrm{PGC\_1alpha\_1}$ $\mathrm{K\_CREB\_toCREBp}\mathrm{CREB}\mathrm{CaMKII}\mathrm{CaMKKII}\mathrm{AMPK\_2\_2\_4}-\mathrm{K\_CREBp\_toCREB}\mathrm{CREB\_1}$ $\mathrm{K\_CRTCp\_toCRTC}\mathrm{CRTC}\mathrm{Calcineurin}-\mathrm{K\_CRTC\_toCRTCp}\mathrm{CRTC\_1}$ $\mathrm{K\_maturation\_PGC1a\_prot}\mathrm{PGC1a\_prot\_cyt}$ $\mathrm{K\_transport\_cyt\_to\_nucl}\mathrm{PGC1a\_prot\_maturated}$ $\mathrm{K\_degr\_mRNA\_ppargc1a}\mathrm{PPARGC1A\_1}$ $\mathrm{Vf\_PPARGC1A\_toPPARGC1Ap}\frac{\mathrm{K\_basal\_PPARGC1A}+\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h+\mathrm{W\_bind\_CREB\_CRTC}\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h\left(\frac{\mathrm{CRTC\_1}}{\mathrm{K\_bind\_CRTC}}\right)^{\mathrm{h1}}}{1.0+\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h+\mathrm{W\_bind\_CREB\_CRTC}\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h\left(\frac{\mathrm{CRTC\_1}}{\mathrm{K\_bind\_CRTC}}\right)^{\mathrm{h1}}}\frac{\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_1\_CREB}}\right)^h}{1.0+\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_1\_CREB}}\right)^h}$ $\mathrm{K\_PGC1a\_prot\_syn}\mathrm{PPARGC1A\_1}$ $\mathrm{K\_transport\_nucl\_to\_cyt}\mathrm{PGC1a\_delay}$ $\mathrm{K\_degr\_PGC1a\_prot}\mathrm{PGC1a\_func\_prot}$ $\frac{\mathrm{K\_basal\_X}+\left(\frac{\mathrm{PGC1a\_func\_prot}}{\mathrm{K\_bind\_PGC1a\_func\_prot}}\right)^{\mathrm{h\_X}}}{1.0+\left(\frac{\mathrm{PGC1a\_func\_prot}}{\mathrm{K\_bind\_PGC1a\_func\_prot}}\right)^{\mathrm{h\_X}}}$ $\mathrm{K\_degr\_mRNA\_X\_fact}\mathrm{PPARGC1A\_3}$ $\frac{\mathrm{K\_basal\_NR4A2}+\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h+\mathrm{W\_bind\_CREB\_CRTC}\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h\left(\frac{\mathrm{CRTC\_1}}{\mathrm{K\_bind\_CRTC}}\right)^{\mathrm{h1}}}{1.0+\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h+\mathrm{W\_bind\_CREB\_CRTC}\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_CREB}}\right)^h\left(\frac{\mathrm{CRTC\_1}}{\mathrm{K\_bind\_CRTC}}\right)^{\mathrm{h1}}}\frac{\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_1\_CREB\_NR4A2}}\right)^h}{1.0+\left(\frac{\mathrm{CREB\_1}}{\mathrm{K\_bind\_1\_CREB\_NR4A2}}\right)^h}$ $\mathrm{K\_degr\_mRNA\_nr4a2}\mathrm{NR4A3\_gene\_mRNA}$ $\mathrm{time}> 300.0$ $5.0$ $\mathrm{time}> 360.0$ $1.0$