The Role of Hydrodynamic Parameters in the Forming of Low-Frequency Oscillations in Arterial Blood Pressure in Human
Grinevich A.A., Tankanag A.V., Chemeris N.K.
Institute of Cell Biophysics of RAS, Pushchino, Russia
Abstract. The mechanism of forming of low-frequency oscillations in the human cardiovascular system is a burning issue today. The current paper considers a hypothesis of hydrodynamic nature of these oscillations, which are formed without the involvement of autonomous control of the cardiovascular system from the autonomic nervous system. The developed reduced hydrodynamic model was used to study the system response on additive periodic perturbation of wide-ranged frequencies that affects the performance of the heart pump, as well as the role of hydrodynamic parameters of the cardiovascular bed in this process. It was shown that low-frequency perturbation of pump wall rigidity forms low-frequency oscillations in the arterial part of the cardiovascular flow without autonomous control, with the maximum amplitude observed at frequency close to 0.1 Hz.
Key words: cardiovascular system, pressure oscillations, blood flow oscillations, mathematical modeling.