Russian version English version
Volume 16   Issue 2   Year 2021
Trusov P.V.1,2, Zaitseva N.V.1, Tsinker M.Yu.1, Nekrasova A.V.2

Mathematical Model of Airflow and Solid Particles Transport in the Human Nasal Cavity

Mathematical Biology & Bioinformatics. 2021;16(2):349-366.

doi: 10.17537/2021.16.349.

References

  1. Brunekreef B., Holgate S.T. Air pollution and health. Lancet. 2002;360:1233–1242. doi: 10.1016/S0140-6736(02)11274-8
  2. Zaitseva N.V., Ustinova O.Iu., Aminova A.I. Gigienicheskie aspekty narusheniia zdorov'ia detei pri vozdeistvii khimicheskikh faktorov sredy obitaniia (Hygienic aspects of children's health disorders under the influence of chemical factors of the environment). Ed. Zaitseva N.V. Perm', 2011. 489 p. (in Russ.).
  3. Xing Y.-F., Xu Y.-H., Shi M.-H., Lian Y.-X. The impact of PM2.5 on the human respiratory system. Journal of Thoracic Disease. 2016;8(1):E69–E74. doi: 10.3978/j.issn.2072-1439.2016.01.19
  4. Vlasova E.M., Vorobeva A.A., Ponomareva T.A. Peculiarities of cardiovascular pathology formation in workers of titanium-magnesium production. Russian Journal of Occupational Health and Industrial Ecology. 2017;9:38 (in Russ.).
  5. Tikhonova I.V., Zemlyanova M.A., Kol'dibekova Yu.V., Peskova E.V., Ignatova A.M. Hygienic assessment of aerogenic exposure to particulate matter and its impacts on morbidity with respiratory diseases among children living in a zone influenced by emissions from metallurgic production. Health Risk Analysis. 2020;3:61–69. doi: 10.21668/health.risk/2020.3.07.eng
  6. Vlasova E.M., Ustinova O.Yu., Nosov A.E., Zagorodnov S.Yu. Peculiarities of respiratory organs diseases in smelters dealing with titanium alloys under combined exposure to fine-disperse dust and chlorine compounds. Hygiene and Sanitation. 2019;98(2):153–158 (in Russ.). doi: 10.18821/0016-9900-2019-98-2-153-158
  7. Grebenev A.L. Propedevtika vnutrennikh boleznei (Propedeutics of Internal Medicine). Moscow, 2001. 592 p. (in Russ.).
  8. Shkliar B.S. Diagnostika vnutrennikh boleznei (Diagnostics of internal diseases). Kiev, 1972. 516 p. (in Russ.).
  9. Trusov P.V., Zaitseva N.V., Kiryanov D.A., Kamaltdinov M.R., Cinker M.Ju., Chigvintsev V.M., Lanin D.V. A Mathematical model for evolution of human functional disorders influenced by environment factors. Mathematical Biology and Bioinformatics. 2012;7(2):589–610 (in Russ.). doi: 10.17537/2012.7.589
  10. Trusov P.V., Zaitseva N.V., Tsinker M.Yu. Modeling of human breath: conceptual and mathematical statements. Mathematical Biology and Bioinformatics. 2016;11(1):4–80 (in Russ.). doi: 10.17537/2016.11.64
  11. Kamaltdinov M.R. 3D modeling of antroduodenal zone motility of digestive track for the purpose of health risks evaluation with peroral exposition to chemicals. Health Risk Analysis. 2014;2:68–75. doi: 10.21668/health.risk/2014.2.08.eng
  12. Kiryanov D.A., Lanin D.V., Chigvintsev V.M. Mathematical model of immune and neuroendocrine systems functioning with regard to evolution of organ synthetic function violations. Health Risk Analysis. 2015;3:68–72. doi: 10.21668/health.risk/2015.3.10.eng
  13. Trusov P.V., Zaitseva N.V., Tsinker M.Yu., Babuskina A.V. Modelling dusty air flow in the human resperatory tract. Russian Journal of Biomechanics. 2018;22(3):301–314 (in Russ.).
  14. Trusov P.V., Zaitseva N.V., Tsinker M.YU. On modeling of airflow in human lungs: constitutive relations to describe deformation of porous medium. PNRPU Mechanics Bulletin. 2020;4:165–174 (in Russ.). doi: 10.15593/perm.mech/2020.4.14
  15. Brüning J., Hildebrandt T., Heppt W., Schmidt N., Lamecker H., Szengel A., Amiridze N., Ramm H., Bindernagel M., Zachow S., Goubergrits L. Characterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity. Scientific Reports. 2020;10(1):3755. doi: 10.1038/s41598-020-60755-3
  16. Ganimedov V.L., Muchnaya M.I., Sadovskii A.S. Air flow in the human nasal cavity. Results of mathematical modelling. Russian Journal of Biomechanics. 2015;19(1):31–44.
  17. Fomin V.M., Vetlutsky V.N., Ganimedov V.L., Muchnaya M.I., Shepelenko V.N., Melnikov M.N., Savina A.A. Air flow in the human nasal cavity. Journal of Applied Mechanics and Technical Physics. 2010;51(2):233-240. doi: 10.1007/s10808-010-0033-y
  18. Sadovskii A.S., Bosykh L.Iu., Ganimedov V.L., Muchnaia M.I. In: XI Vserossiiskii s''ezd po fundamental'nym problemam teoreticheskoi i prikladnoi mekhaniki (The XI All-Russian Congress on Basic Problems of Theoretical and Applied Mechanics): abstracts. 2015. P 3298–3300 (in Russ.).
  19. Ganimedov V.L., Muchnaya M.I. Numerical simulation of particle deposition in the human nasal cavity. Thermophysics and Aeromechanics. 2020;27(2):303–312. doi: 10.1134/S0869864320020122
  20. Voronin A., Luk'yanov G., Neronov R. Computational modeling of airflow in nonregular shaped channels. Scientific and Technical Journal of Information Technologies, Mechanics and Optics. 2013;3(85):113–118.(in Russ.).
  21. Neronov R.V., Luk’yanov G.N., Rassadina A.A., Voronin A.A., Malyshev A.G. The effect of the nasal cavity form on air flow distribution during inhalation. Russian Otorhinolaryngology. 2017;1(86):83–94 (in Russ.). doi: 10.18692/1810-4800-2017-1-83-94
  22. Lukyanov G.N., Voronin A.A., Rassadina A.A. Simulation of convective flows in irregular channels on the example of the human nasal cavity and paranasal sinuses. Technical Physics. 2017;62(3):484–489. doi: 10.1134/S1063784217030136
  23. Tang H., Tu J.Y., Li H.F., Au-Hijleh B., Xue C.C., Li C.G. Dynamic Analysis of Airflow Features in a 3D Real-Anatomical Geometry of the Human Nasal Cavity. 15th Australasian Fluid Mechanics Conference. Sydney, Australia, 2004. https://www.aeromech.usyd.edu.au/15afmc/proceedings/papers/AFMC00174.pdf (accessed 15.06.2021).
  24. Zamankhan P., Ahmadi G., Wang Z., Hopke P.K., Cheng Y-S., Su W.S., Leonard D. Airflow and Deposition of Nano-Particles in a Human Nasal Cavity. Aerosol Science and Technology. 2006;40:463–476. doi: 10.1080/02786820600660903
  25. Saghaian S.E., Azimian A.R., Jalilvand R. Dadkhah S., Saghaian S.M. Computational analysis of airflow and particle deposition fraction in the upper part of the human respiratory system. Biology, Engineering and Medicine. 2018;3(6):6–9. doi: 10.15761/BEM.1000155
  26. Doorly D.J., Taylor D.J., Gambaruto A.M., Schroter R.C., Tolley N. Nasal architecture: form and flow. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 2008. doi: 10.1098/rsta.2008.0083
  27. Doorly D.J., Taylor D.J., Schroter R.C., Mechanics of airflow in the human nasal airways. Respiratory Physiology and Neurobiology. 2008;163:100–110. doi: 10.1016/j.resp.2008.07.027
  28. Inthavong K., Das P., Singh N., Sznitman J. In silico approaches to respiratory nasal flows: A review. Journal of Biomechanics. 2019;97:109434. doi: 10.1016/j.jbiomech.2019.109434
  29. Subramaniam R., Richardson R., Morgan K., Kimbell J., Guilmette R. Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx. Inhalation Toxicology. 1998:91–120. doi: 10.1080/089583798197772
  30. Zhao K., Scherer P.W., Hajiloo S.A., Dalton P. Effect of anatomy on human nasal air flow and odorant transport patterns: Implications for olfaction. Chemical Senses. 2004;29(5):365–379. doi: 10.1093/chemse/bjh033
  31. Shang Y.D., Inthavong K., Tu J.Y. Detailed micro-particle deposition patterns in the human nasal cavity influenced by the breathing zone. Computers and Fluids. 2015;114:141–150. doi: 10.1016/j.compfluid.2015.02.020
  32. Garcia G.J., Bailie N., Martins D.A., Kimbell J.S. Atrophic rhinitis: A CFD study of air conditioning in the nasal cavity. Journal of Applied Physiology. 2007;103:1082–1092. doi: 10.1152/japplphysiol.01118.2006
  33. Ge Q.J., Inthavong K., Tu J.Y. Local deposition fractions of ultrafine particles in a human nasal-sinus cavity CFD model. Inhalation Toxicology. 2012:492–505. doi: 10.3109/08958378.2012.694494
  34. Goodarzi-Ardakani V., Taeibi-Rahni M., Salimi M.R., Ahmadi G. Computational simulation of temperature and velocity distribution in human upper respiratory airway during inhalation of hot air. Respiratory Physiology and Neurobiology. 2016;223:49–58. doi: 10.1016/j.resp.2016.01.001
  35. Hörschler I., Brücker C., Schr¨oder W., Meinke M., Investigation of the impact of the geometry on the nose flow. European Journal of Mechanics, B/Fluids. 2006;25:471–490. doi: 10.1016/j.euromechflu.2005.11.006
  36. Wen J., Inthavong K., Tu J., Wang S. Numerical simulations for detailed airflow dynamics in a human nasal cavity. Respiratory Physiology and Neurobiology. 2008;161:125–135. doi: 10.1016/j.resp.2008.01.012
  37. Lindemann J., Brambs H.-J., Keck T., Wiesmiller K.M., Rettinger G., Pless D. Numerical simulation of intranasal airflow after radical sinus surgery. American Journal of Otolaryngology – Head and Neck Medicine and Surgery. 2005;26(3):175–180. doi: 10.1016/j.amjoto.2005.02.010
  38. Mai I.V., Zaitseva N.V., Ulanova T.S., Vekovshinina S.A., Zagorodnov S.Iu., Kokoulina A.A., Sedusova E.V., Popova E.V. Atlas promyshlennykh pylei. Pyli mashinostroitel'nykh, metallurgicheskikh, gornodobyvaiushchikh, gorno-pererabatyvaiushchikh proizvodstv i predpriiatii tsvetnoi metallurgii (Industrial dust atlas. Dust from engineering, metallurgical, mining, mining and processing industries and non-ferrous metallurgy enterprises). Perm', 2014. 285 p. (in Russ.).
  39. Liu Y., Johnson M.R., Matida E.A., Kherani S., Marsan J. Creation of a standardized geometry of the human nasal cavity. J. Appl. Physiol. 2009;106:784–795. doi: 10.1152/japplphysiol.90376.2008
  40. Borziak E.I., Volkova L.I., Dobrovol'skaia E.A., Revazov V.S., Sapin M.R. Anatomiia cheloveka (Human anatomy). Ed. M.R. Sapin. Moscow, 1993. Vol. 1. 544 p. (in Russ.).
  41. Liu Y., Matida E.A., Johnson M.R. Experimental measurements and computational modeling of aerosol deposition in the Carleton-Civic standardized human nasal cavity. Journal of Aerosol Science. 2010;41:569–586. doi: 10.1016/j.jaerosci.2010.02.014
  42. Inthavong K., Wen J., Tu J., Tian Z. From CT scans to CFD modelling-fluid and heat transfer in a realistic human nasal cavity. Eng. Appl. Comput. Fluid Mech. 2009;3(3):321–335. doi: 10.1080/19942060.2009.11015274
  43. Garcia J.M., Schroeter J.D., Kimbell J.S. Sniffing out airflow and transport processes in the nasal cavity. Fluent News Appl. Comput. Fluid Dynamics. 2006;15(3):3–5.
  44. Katsnel'son B.A., Alekseeva O.G., Privalova L.I., Polzik E.V. Pnevmokoniozy: patogenez i biologicheskaia profilaktika (Pneumoconiosis: pathogenesis and biological prevention). Ekaterinburg, 1995. 325 p.(in Russ.).
  45. Brain J.D., Valberg P.A. Models of lung retention based on the ICRP task group report. Arch. Environ. Health. 1974;28(1):1–11. doi: 10.1080/00039896.1974.10666424
Table of Contents Original Article
Math. Biol. Bioinf.
2021;16(2):349-366
doi: 10.17537/2021.16.349
published in Russian

Abstract (rus.)
Abstract (eng.)
Full text (rus., pdf)
References Translation into English
Math. Biol. Bioinf.
2023, 18(Suppl):t1-t16
doi: 10.17537/2023.18.t1

Full text (eng., pdf)

 

  Copyright IMPB RAS © 2005-2024