Stem Multiplets: a New Approach to the Description of Tertiary RNA Motifs
Baulin E.F, Roytberg M.A.
Institute of Mathematical Problems of Biology, Russian Academy of Sciences, Pushchino, Moscow region, 142290, Russia
Faculty of Computer Science, National Research University “Higher School of Economics”, Moscow, 101000, Russia
Educational Center of Mathematical Biology, Pushchino State Institute of Natural Sciences, Pushchino, Moscow region, 142290, Russia
Moscow Institute of Physics and Technology (State University), Dolgoprudny, Moscow region, 141700, Russia
Abstract. We present an approach allowing one to describe complex fragments of RNA tertiary structure. The approach is based on the definition of a stem multiplet, i.e. a structural element formed by two or more interacting stems. Using previously developed database of RNA structures (
http://server3.lpm.org.ru/urs/) we have revealed all stem multiplets presented in the PDB database.
Key words: 3D RNA structure, multiplet, stem, pseudoknot, link, graph.