Russian version English version
Volume 11   Issue 1   Year 2016
Phenotypic Variability of Bacterial Cell Cycle: Mathematical Model

Likhoshvai V.A., Khlebodarova T.M.

Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia 
Novosibirsk State University, Novosibirsk, Russia

Abstract. The results of the study of mechanisms of different cell phenotypes occurrence in a genetically homogenous population using the bacterial cell cycle model are presented. It was shown that phenotypic variability represents an internal, immanent property of bacteria. The basis of this phenomenon is universal non-linear properties of the conjugated transcription-translation system, that controls all cellular processes. Phenotypic variability occurs in a simple, deterministic, self-reproducing system under the uniform transmission of the structural components to the daughter cells during division and in the absence of any special control mechanisms of molecular-genetic processes and enzymatic reactions.
 
Key words: bacteria, cell cycle, modelling, phenotypic variability.
 
Table of Contents Original Article
Math. Biol. Bioinf.
2016;11(1):91-113
doi: 10.17537/2016.11.91
published in Russian

Abstract (rus.)
Abstract (eng.)
Full text (rus., pdf)
References Translation into English
Math. Biol. Bioinf.
2017;12(Suppl.):t23-t44
doi: 10.17537/2017.12.t23

Full text (eng., pdf)

 

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